A T1 hyperintense perilesional signal aids in the differentiation of a cavernous angioma from other hemorrhagic masses.
نویسندگان
چکیده
BACKGROUND AND PURPOSE A cavernous angioma is a developmental vascular malformation with a high risk of hemorrhage. The purpose of this work was to retrospectively determine whether an MR sign of T1 hyperintense perilesional signal intensity is useful for the differentiation of cavernous angioma from other hemorrhagic cerebral masses. MATERIALS AND METHODS The institutional review board approved this study. We retrospectively evaluated the MR images of 72 patients with acute or subacute cerebral hemorrhagic lesions with perilesional edema (29 cavernous angiomas, 13 glioblastomas, 1 oligodendroglioma, 16 metastatic tumors, and 13 intracerebral hemorrhages) for the presence of T1 hyperintense perilesional signal intensity. In addition, T1 signal intensities of a perilesional edema were quantitatively analyzed. In cavernous angiomas, volumes of hemorrhagic lesions and perilesional edemas, lesion locations, presence of contrast enhancement, and time intervals between symptom onset and MR imaging were also assessed. Data were analyzed using unpaired t test or Fisher exact test. RESULTS T1 hyperintense perilesional signal intensity sign was found in 18 (62.1%) of 29 cavernous angiomas, in 1 (6.3%) of 16 metastases, and in 0 primary brain tumors or intracerebral hemorrhages. Sensitivity, specificity, and positive predictive value of this sign for cavernous angioma were 62%, 98%, and 95%, respectively. The perilesional T1 hyperintensity was significantly higher in cavernous angiomas (P = .045) than in normal white matter. Perilesional edema volumes were larger in cavernous angiomas with the MR sign than in cavernous angiomas without the sign (P = .009). CONCLUSION When the MR sign of T1 hyperintense perilesional signal intensity is present, there is a high probability of cavernous angioma being present in the brain, and this MR sign may be helpful for differentiating cavernous angioma from hemorrhagic tumors and intracerebral hemorrhages.
منابع مشابه
Cavernous angioma of the cavernous sinus: imaging findings.
Cavernous angiomas (cavernomas) of the cavernous sinus are uncommon, with only scattered reports in literature. Unlike their parenchymatous counterparts, they are intensely enhancing para-sellar masses, iso/hypointense in T1- and hyperintense in T2-weighted images. Differential diagnosis with para-sellar meningiomas and schwannomas can be difficult. We report three cases of this condition, desc...
متن کاملPitfall in Differentiation of Hemorrhagic Vs. Fatty Lesions in Female Pelvis Using Fat Saturated Sequences With Inversion Recovery – Role of T1 FATSAT Sequence – A Case Report with Radiological Review
T1 hyperintense structure in female pelvis can be either a hemorrhagic lesion or fat containing lesion. FATSAT technique is integral part of workup of any T1 hyperintense structures in female pelvis for differentiation of hemorrhagic lesion and fat containing mature ovarian teratoma for tissue characterization. We present a case of hematometra with blood in bilateral fallopian tubes due to cerv...
متن کاملA Case of Atopic Myelitis with Cervical Cavernous Angioma
Atopic myelitis, a type of myelitis which appears in patients with elevated serum levels of immunoglobulin E (IgE), occurs more commonly in the cervical spinal cord, but this mechanism has not yet been elucidated. Herein, we experienced a case of atopic myelitis developed during the growth of cervical cavernous angioma caused by bleeding. A 37-year-old woman suffered from hand swelling caused b...
متن کاملOptic chiasmal cavernous angioma: A rare suprasellar vascular malformation
BACKGROUND Suprasellar cavernous malformation in the optic pathway is not commonly encountered. To date, there are only few reports present in the literature. CASE DESCRIPTION The authors report a rare case of suprasellar optic pathway cavernous malformation in a 33-year-old female who presented with progressive visual loss. Her imaging revealed a large heterogeneous, hyperintense, hemorrhagi...
متن کاملCharacterization of T1 hyperintense renal lesions with diffusion-weighted imaging: preliminary experience
Introduction T1 hyperintense renal lesions may represent hemorrhagic/proteinaceous cysts or neoplasms. The visual assessment of enhancement of these lesions can be difficult, and signal intensity measurements before/after contrast injection and qualitative analysis of enhancement with image subtraction can be used in that purpose. We wanted to determine the accuracy of apparent diffusion coeffi...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- AJNR. American journal of neuroradiology
دوره 29 3 شماره
صفحات -
تاریخ انتشار 2008